Autism Spectrum Disorder and Stem Cells

Which stem cells are used to treat Autism Spectrum Disorder (ASD)

ProGenaCell stem cells are derived from human umbilical cord tissue. Umbilical cords are donated by mothers contemporaneous to a healthy birth. All umbilical cord-derived stem cells are screened for viruses and bacteria according to international blood bank standards.

Umbilical cord-derived stem cells allow our physicians to administer uniform doses and avoid harvesting stem cells from the patient, which, can especially difficult for children. Because they are collected right after (normal) birth, fresh umbilical cord-derived cells are much more potent than their "older" counterparts like fat-derived cells for instance. Cord tissue-derived mesenchymal stem cells pose no rejection risk because the body does not recognize them as foreign.

Our laboratory undertakes a very disciplined screening process to identify cells know to have the best anti-inflammatory activity, the best immune modulating capacity, and the best ability to stimulate regeneration."

Autism Spectrum Disorder

What are the advantages of treating ASD with fresh umbilical cord tissue derived stem cells?

  • Since mesenchymal stem cells are immune system privileged, cell rejection is not an issue and Human Leukocyte Antigen (HLA) matching is not necessary.
  • The stem cells with the best anti-inflammatory activity, immune modulating capacity, and ability to stimulate regeneration can be screened and selected.
  • Allogeneic stem cells can be administered multiple times over the course of days in uniform dosages that contain high cell counts.
  • Umbilical cord tissue provides an abundant supply of mesenchymal stem cells.
  • No need to collect stem cells from the patient's hip bone or fat under anesthesia, which especially for small children and their parents, can be an unpleasant ordeal.
  • There is substantial evidence showing that umbilical cord-derived neuronal stem cells are more robust than neuronal stem cells from other sources.
  • No need to administer chemotherapy drugs like Granulocyte-colony stimulating factor (G-CSF or GCSF) to stimulate the bone marrow to produce granulocytes and stem cells and release them into the bloodstream.

ProGenaCell Stem Cells: Are they approved?

Fresh cord blood neuronal stem cells that were isolated and grown in our global laboratories to create master cell banks are identical to cells currently used in the United States under US FDA regulation.

These cells serve as the starting material for cellular products used in MSC clinical trials for two Duchenne's muscular dystrophy patients under US FDA's designation of Investigational New Drug (IND) for single patient compassionate use. (IND 16026 DMD Single Patient).

Will The Patient Reject This Type of Stem Cell?

The body's immune system is unable to recognize cord blood stem cells as foreign and therefore not rejected. Cord blood stem cells have been administered thousands of times at ProGenaCell approved clinics with no rejection (graft vs. host disease). As a matter of fact, allogeneic (not the patient's own) mesenchymal stem cells similar to neuronal cells are approved to treat graft vs. host disease in Canada and New Zealand.

Cord blood stem cells also proliferate/differentiate more efficiently than "older" cells, such as those found in the fat and therefore, they are considered to be more "potent".

How Are The Stem Cells Administered For ASD Treatment?

The umbilical cord-derived stem cells are administered by trained physicians via intranasal and intravenous injection.

Stem Cell Treatment: ASD Protocols

Treatment protocol will be assigned by staff physicians after the patient has submitted all requested medical information and received approval. A patient's recommended protocol may differ from the example given below.

  • Treatment length (Monday – Friday): 5 Days.
  • Physical examination and blood testing: Monday.
  • Two infusions of cord blood stem cells: Tuesday and Wednesday

What about Patient Follow-Up?

Proper follow-up is an essential part of ASD palsy treatment process. Our primary goal is to ensure that your child is progressing safely. Regular follow-up also enables us to evaluate efficacy and improve our ASD treatment protocols based on patient reported outcomes.

Therefore, our medical staff will be contacting you after 1 month, 3 months, 6 months, and 1 year to monitor your child's progress.

Meet Luella, an ASD Patient

Start your treatment today!

Speak with a qualified ProGenaCell Representative today about the benefits of ProGenaCell Cell Therapy.

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